Background & Objectives: Oral and maxillofacial surgical procedures often can produce open wounds. Oral mucosal or skin grafts are used to cover the open wounds to prevent microbial infection, excessive fluid loss, foreign material contamination and wound contracture optimize the rate of healing. In this study collagen sheet was used to cover the wounds intraorally for its effectiveness & usefulness in promoting wound healing.

Methods: Evaluation of collagen sheet as biological dressing material was used in 20 patients for intraoral denuded areas following excision of premalignant lesions & conditions such as leukoplakia, lichen planus and oral sub mucous fibrosis. The efficacy of collagen membrane in promoting haemostasis, relieving pain, inducing granulation, preventing infection, assisting in rapid epithelization at wound site and minimizing scar were assessed.

Results: Collagen for intraoral wounds is proved to be very effective & very potent in promoting haemostasis & relieving pain. In none of the cases any adverse reaction to the collagen was observed proving its safety as a biological dressing.

Conclusion: It is an effective biological dressing in promoting hemostasis, relieving pain, preventing wound contamination and induces granulation tissue and epithelization thereby reduces degree of scarring and tissue contracture and avoiding second surgical site.