IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-11-13375 Original Research Paper Effect of Dexmedetomidine or Clonidine on the characteristics of Bupivacaine spinal block in surgeries below umbilicus Hathiwala Dr. Pragna Vachharajani Dr. November 2017 6 11 01 02 ABSTRACT

 This study aimed to compare the onset and duration of sensory and  motor block, postoperative analgesic requirements as well as hemodynamic stability following intrathecal bupivacaine with either dexmedetomidine or clonidine. 90 patients of ASAgrade I and II scheduled for lower abdominal surgery were divided into three groups. Each patient was given 3ml of 0.5% of hyperbaric bupivacaine and 0.1ml of normal saline(group BP), 10μg of dexmedetomidine(group BD) and 15μg of clonidine(group BC). Addition of these adjuvants  to intrathecal hyperbaric Bupivacaine (0.5%) significantly prolongs the duration of sensory and motor block along with prolong postoperative analgesia & perioperative hemodynamic stability