Introduction:  Urinary tract infection (UTI) represents one of the most common bacterial infection. Emerging antimicrobial resistance among the predominant uropathogens, limits the available treatment options.

Aims : To study the  microbiological etiology and  the antimicrobial susceptibility pattern of the uropathogens in a teaching hospital in north India, Faridabad.

Materials and Methods: The  study was carried out from April, 2016 to September, 2016. During this period, Antimicrobial sensitivity test was performed on all uropathogens.

Results:  211 isolates included 12.1%  gram positive and 87.8% gram negative organisms.  The most common organism was Escherichia coli (64%) followed by Entrococcus spp (11.8%),Klebsiella spp (6.6%), Staphylococcus aureus(6.1%). Among gram negative organisms, maximum resistance was observed for ampicillin (87–89%), cotrimoxazole (57–63%), cephalosporins (35–82%),  fluoroquinolones(35–62%) and nitrofurantion (27–57%).    Enterococcus spp had high level aminoglycoside resistance as 60%. 32% S.aureus isolates were MRSA and 20% were resistant to Glycopeptides.

 Conclusion: Emerging bacterial drug resistance has both clinical and financial implications for  therapeutic purpose. Spectrum of bacterial drug resistance in an institution is important for epidemiological as well as clinical purposes