(i) Objective:      To determine the effect of microcytic anemia on HbA1C values in  individuals without diabetes.

(ii) Methods:    The study was conducted as a clinical non–interventional observation study.  A sample of 200 patients with MCV less than 80 fL, FPG less than 100mg/dL was selected and in them HbA1C test was carried out using HPLC method. A control population of 40 patients with normal MCV and FPG less than  100 mg/dL was also  taken and in them also HbA1C was studied.

(iii) Result:        Out of the  200 cases studied 98 were males and 102 were females.  The mean age for cases was 51.87 years. 28% patients had severe anemia, 64.5% patients had moderate anemia and 7.5% patients had mild anaemia. Mean MCV for cases were 71.86fL. A significant negative correlation has been found out between  HbA1C and haemoglobin levels  and between HbA1C and MCV.

(iv) Conclusion:  There is a definite negative correlation between MCV and HbA1C in the study population. A significant correlation was also found between haemoglobin and HbA1C value.