Aims and Objectives: To study cardiovascular risk factors in patients of chronic kidney disease (CKD) and correlation with various clinical, radiological and biochemical parameters. Material and Methods: A total number of 60 patients with CKD aged 21–60 years were recruited from the Department of Nephrology who fulfilled the inclusion criterion, after taking informed consent. Results: Increased levels of serum creatinine and blood urea were associated with increased severity of disease. Severity of anemia was related to the duration and extent of CKD. Low serum calcium levels and high phosphate levels were associated with adverse outcome. Lipoprotein  (A) and carotid artery intimal thickness showed positive relation with progression of CKD. Conclusion: ESRD patients are associated with deranged metabolic parameters which leads to increased cardiovascular risk. The increase in cardiovascular risk among patients of CKD is secondary to accumulation of risk factors.