IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-12-13670 Original Research Paper FOUR YEAR RETROSPECTIVE STUDY OF CERVICAL CANCER IN A TERTIARY CARE CENTRE SURESH Dr. December 2017 6 12 01 02 ABSTRACT

 Cancer of the cervix uteri  is  the most common cancer among women

 In India .Although screening procedure like pap smear is being employed for

early detection ,cancer cervix remains as one of leading cause of death in

 female malignancies..The association of several risk factors  including

promiscuity, multiple sexual partners, and intercourse at an early age, oral

contraceptives, smoking and infection by human papillomavirus are well known

  in the developmentof invasive cervical cancer. The present retrospective clinico

pathological study is undertaken to analyse the clinical presentation, age

incidence and histomorphological  pattern of  carcinoma cervix.

MATERIALS AND METHODS:During the four  year period of study (June 2009 to October 2013) ,a total of 173  cervical biopsies, which were diagnosed as invasive carcinoma of cervix in the Department of Pathology, in a tertiary care hospital, were included in the study. Four micrometer thickness sections from paraffin embedded blocks were subjected to routine Haematoxylin and Eosin staining procedure. The data was analyzed for the age incidence, clinical presentation, histopathological types of carcinoma cervix .

RESULTS: Out of 173 cases of invasive cervical carcinoma analyzed 163 cases were of Squamous Cell carcinoma (94.21%) out of which large cell nonkeratinising  SCC account for 95.3% & Large cell keratinizing account for 4.70% of cases .Seven cases of (4.04%) of adenocarcinoma and one case of glassy cell carcinoma and two cases of adenosquamous were also encountered. The highest incidence of carcinoma cervix was in the fourth to fifth decade with bleeding with white discharge per vaginum as the most common presenting complaint.

CONCLUSION: INDIA has a huge burden of cancer cervix and a multipronged screening modalities like conventional Pap, Liquid based cytology and HPV DNA testing are necessary to prevent and remove this scourge from our country