Breast carcinoma is the second most common carcinoma in women and account for 22% of all female cancers, which is more than twice the prevalence of cancer in women at any other site. Recent information suggests that globally after lung cancer, the carcinoma of the breast is the second leading cause of cancer related death and is the most common cancer among women excluding the non–melanoma skin cancers. India accounts for nearly six percent of deaths due to breast cancer in the world and also that one out of every 22 women in India are diagnosed with breast cancer every year. 

The aim of this study is to determine the role of oestrogen receptor [ER] and progesterone receptor [PR] status in choice of treatment for further management of patients with breast carcinoma from December 2015 to June 2017,Rajarjeswari Medical College and hospital. Evaluation of ER and PR status with core needle biopsy and post–surgical histological specimen. Correlation of ER and PR status incidence with other prognostic factors: a) Patient age, b) Age at menarche, c) Age at menopause, d) Parity of patient, e) Tumor size, f) Number of lymph nodes. 

Methods:

This study was carried out on patients admitted in the General Surgery Department from December 2015 to June 2017, has been approved by local research ethical committee.

Results

A low incidence of ER–positive and high incidence of ER–negative tumours. A higher incidence of poorly differentiated and a lower incidence of well–differentiated tumours, tumour grade was independent of age, menopausal status, histopathology and stage. 

Conclusion

The women with oestrogen and progesterone receptor positive status can opt for hormonal therapy, which will be beneficial for them. The women with oestrogen and progesterone receptor negative status, hormonal therapy will be ineffective.