BACKGROUND : Ultrasonography forms an integral part and is the primary imaging modality in thyroid disorders.

AIM: To evaluate the diagnostic accuracy of ultrasonography in thyroid disorders by correlating with histopathology.

METHOD: The utrasonographic report of 350 consecutive patients who underwent total thyroidectomy was correlated with the histopathology report.

RESULTS: USG had a statistically significant chi–square distribution  of 95.795 by nonparametric ANOVA against variable HPE.  It had a sensitivity, specificity, positive and negative predictive values for malignancy of 86.05%, 94.94%, 95.9%, 83.8% respectively.

CONCLUSION: The wide variations between the reports of USG and HPE could be due to overlapping areas and the gray zones in the two systems which can be overcome by a perfect understanding between the surgeon, radiologist and the pathologist.