Background: The sexually transmitted diseases (STD) are a group of communicable diseases that are predominantly by sexual contact and caused by wide range of bacterial, viral, protozoal and fungal agents and ectoparasites. More than 1 million STIs are acquired every day. Each year, there are estimated 357 million new infections.  Aims and objectives: To assess the socio clinico– epidemological profile of the patients attending SURAKSHA Clinic at GMCH. Methods: present hospital based cross–sectional study was conducted in the SURAKSHA Clinic of GMCH for a period of three months from 15–06–2016 to 15–09–16. Data of 276 patients coming to SURAKSHA Clinic were collected by purposive sampling. Results:  Out of 276 patients of STI/RTI patients,52.17% were females and 47.83% were males. Most common syndrome among female was vaginal discharge (73.61%) followed by lower abdominal pain(66.67%). Among males most common syndrome was urethral discharge (57.58%). Conclusions: STI/RTI is more prevalent in females as compared to males possibly because of certain established biological factors.. Proper understanding of pattern of STI in a particular region in very important for proper planning of STI control. This can be further reduced by education, awareness and syndromic treatment of RTI as per NACO guidelines.