Abstract

Chronic periodontitis can be treated effectively by mechanical debridement and the clinical and microbial benefit of mechanical debridement can be increased by local application of antimicrobials agents. Chlorhexidine is an effective antimicrobial, antiplaque and antigingivits agent and its application can enhance periodontal therapy. It was initially utilized as anti–septic agent but with continued research its effective role as an oral antiplaque agent was discovered. Chlorhexidine is not effective as an antimicrobial but has the property of substantivity and fewer side effects compared to other chemical plaque control agents. The pharmacology of Chlorhexidine and suggestions for its indicated uses, its adverse effects and various forms in which it is available are outlined in this review.