The ultimate goal in the practice of endodontics is to debride and obturate the canal as efficiently and three dimensionally as possible in order to prevent re–infection. But some teeth with incompletely formed apex differ from providing routine treatment. Major challenges associated with endodontic treatment of immature teeth with necrotic pulp and wide open apices are achieving complete debridement, canal disinfection and most important optimal sealing of the root canal system. So, a procedure called apexification introduced to induce a calcified barrier in a root with an open apex but having thin dentinal walls. The aim of the procedure is to limit bacterial infection and create an environment conducive to the production of mineralized tissue in the apical region. Many materials like calcium hydroxide and mineral trioxide aggregate (MTA) have been reported to successfully stimulate apexification.