IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-1-13968 Original Research Paper CLINICO–MICROBIOLOGICAL STUDY OF RUBELLA IN PREGNANT FEMALES WITH BAD OBSTETRIC HISTORY (BOH) Singh Dr. Arth Nath Dube Dr. January 2018 7 1 01 02 ABSTRACT

 

Research finding indicated that Rubella IgM prevalence was 2.27% and that of IgG was 67.5%. The distribution showed increase of IgG and IgM antibodies with increase in the number of abortions. In Normal group patients (N) IgG was mostly positive for patients with Gestational age 3rd Trimester (29–40 weeks). The distribution also showed that in this group IgG was most positive for those in the age group 26–30 years. In group A1 patients again IgG was found to be most  positive for those with gestational age 3rd Trimester (29–40 weeks). In this group IgG was mostly positive for those in the age group of 20–25 years. The distribution for group A2 patients showed an increase of IgG antibodies for those with Gestational age 3rd Trimester (29–40 weeks). The patients of this group also showed increased IgG antibodies in the age group 20–25 years .

 High prevalence of Rubella IgG antibodies indicates prior exposure , infection or vaccination. There was only two cases of  Rubella IgM antibody,one of which belonged to group A1 and the other toA2 group.The presence of rubella IgM antibodies in these two patients with history of one and two abortions indicates a close association with rubella infection.Early detection in pregnant women can reduce severity of the disease in the newborn.