IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-1-14025 Original Research Paper STUDY OF OXIDATIVE STRESS AND OVER WEIGHT IN POST MENOPAUSAL WOMEN OF INDIA Jyoti Dr. January 2018 7 1 01 02 ABSTRACT

 

It has been suggested that several medical complications can develop after menopause. Over weight and oxidative stress are the clinical conditions associated with post menopause. Hormonal changes in women are likely to cause some physiological changes which can eventually lead to above clinical state in most of the post menopausal women. The objective of this study is to evaluate the oxidative stress and BMI in post menopausal women of India. We performed a study in post menopausal women aged 60–70 years. (n=45).

 

Oxidative stress was evaluated by measuring the lipid peroxidation product MDA and plasma enzymes involved in antioxidant activity i.e. SOD and catalase in the experimental subjects. We also measured the BMI of subjects for categorizing overweight.

 

Thus post menopause is a physiological state accompanied by increased oxidative stress and weight gain. Marker of oxidative stress MDA increases significantly and also decreased antioxidant enzymes due to their greater utilization is observed. BMI in the range of 22–25 was calculated which is a determinant of overweight. Antioxidant supplementation can prove to be a good adjuvant therapy in controlling oxidative stress.