Background : The CRP protein is well known as an acute phase protein whose concentration increases as a result of inflammatory process. However, in an attempt to improve global cardiovascular risk prediction, considerable interest has focused on detection of low levels of CRP. The CRP seems indeed to be a strong predictor of vascular events. Hence aim of this study is to study hs–CRP level in acute coronary syndrome and to determine the mortality risk associated with serum level of hsCRP

Material and method : A cross–sectional observational study on 55 patients was done in  indoor patients of Department of Medicine, R.I.M.S, Ranchi. The Inclusion criteria was cases of acute coronary syndrome diagnosed clinically and supported by ECG, echocardiography and  cardiac enzyme. Patients suffering from chronic kidney disease and pulmonary disease were  excluded from this study. Immunoturbidimetric method was used for hs–CRP detection.

Results: In our study 19 case (57.54%) is male and 14 case (42.43%) is females were at the age group (30–60), and 81.82% males and 18.18% females were more than 60 years. Out of 55 cases of acute coronary syndrome, 10.92% patient  died. All patients who died had more than 3mg/l hs–CRP level.

Conclusion:Higher mean level of hs–CRP was observed when acute coronary syndrome was present.