Background: Acne vulgaris is one of the most common skin diseases affecting majority of the teens and reaching its pinnacle during adulthood. In some severe cases, it leads to pronounced skin deformity which adversely dampen the self–esteem of the affected which can eventually lead to depression and even suicides. Usually this disease invariably diminishes in twenties but in some cases, it might even persist in thirties, forties and beyond. Majority of females suffer from mild to moderate acne at some stage of life. Androgens cause enlargement and overstimulation of the sebaceous glands in people with acne and this leads to overproduction of sebum coupled with sluggish exfoliation process leads to blocked pores and development of acne, so the present study conducted with objectives to compare hormonal levels of serum testosterone, LH, FSH among patients with and without Acne and to compare the hormonal levels in different categories of acne among study participants.