Reactive arthritis is a sterile oligo–arthritis associated with infection. Chlamydia, Salmonella, Shigella have been postulated as most common organisms associated with Reactive arthritis. Genetic susceptibility, mainly HLA–B27 positivity, plays a key role in the pathogenesis. It is thought that antigen from infectious organisms trigger inflammatory response in synovium in a genetically susceptible host. Two infectious syndromes– genitourinary and gastrointestinal infections have been classically depicted with Reactive arthritis. However, in literature, other sorts of infections have occasionally been described with this form of arthritis. Here we report a case of reactive arthritis associated with HEV infection.