Background: Type 2 Diabetics have an increased susceptibility to opportunistic infections, especially Candidiasis. Candida species have been found in periodontal pockets expressing virulence factors that may contribute for the pathogenesis of Chronic periodontitis (CP). We aimed to investigate the association if any of C.albicans (CA) and other Non–Candida albicans Candida (NCAC) species in CP with and without DM.

Material and Methods: Clinical parameters were recorded and subgingival plaque samples obtained from 45 subjects evenly distributed into 3 groups; Group 1 (Healthy), Group 2 (CP with Type 2 DM) and Group 3 (CP without DM) were cultured on Sabouraud Dextrose Agar, followed by Gram’s staining and Germ tube test.

Results: Microbiological analyses revealed the presence of Candida colonies in the subgingival biofilm of Groups 2 and 3 and were positive for NCAC species only.

Conclusion: Candida co–infection is a plausible etiological factor for CP in Type 2 diabetics and non–diabetics.