•      Introduction Esthesioneuroblastoma (ENB) is a rare malignant neoplasm about 3% . Most of these patients presents in locally advanced stages and require multimodality treatment. Multimodality approach with a risk–adapted strategy is required to achieve good control rates.

•      Objective . This article outlines the various newer details of quality of life assessment in esthioneuroblastoma. The importance of early diagnosis of esthioneuroblastoma.

•      Methodology :A Retrospective study  of  2 years duration with a sample size of 14 cases . Pre–Treatment and 1½ year follow–up questionnaire was given to all the patients who were included in the study.

•      Results – Recorded data shows poor Quality of Life (QOL) soon after diagnosis. Same worsened if the presenting stage was advanced.

Conclusion. Early detection and radio–imaging, with diagnostic nasal examination (DNE) helps in improving the QOL in patients with esthioneuroblastoma