IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-2-14091 Original Research Paper A STUDY OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION IN ISCHEMIC HEART DISEASE–EVALUATION BY DOPPLER ECHOCARDIOGRAPHY Reddy Dr. Dr.K.Naveen Kumar Dr. February 2018 7 2 01 02 ABSTRACT

 Background:  Heart failure is a clinical syndrome characterized by symptoms and signs of increased tissue/organ water and decreased tissue/organ perfusion. Diastolic heart failure is a clinical syndrome characterized by the symptoms and signs of heart failure, a preserved ejection fraction (EF), and abnormal diastolic function Abnormalities in diastolic function can occur in the presence or absence of a clinical syndrome of heart failure and with normal or abnormal systolic function. Therefore, whereas Diastolic Dysfunction describes an abnormal mechanical property, diastolic heart failure describes a clinical syndrome.

Aims & Objectives:

1.      To evaluate significance of left ventricular diastolic dysfunction in ischemic heart

disease.

2.      To evaluate application of Doppler echocardiography in determining left ventricular diastolic dysfunction in ischemic heart disease.

3.      To find out early left ventricular diastolic dysfunction in ischemic heart disease as a marker of impending major cardiac events and to promote the quality of life.

Materials and Methods: 60 cases of ischemic heart disease (unstable angina, anterior wall infarction and inferior wall infarction) admitted to Govt. General Hospital during April 2014 to September 2015 were studied.

Results:  The left ventricular filling studies by Doppler echocardiography done in study and control population were analysed and the results are as follows. In our study patients with IHD, E–velocity (cm/sec) was decreased in study group compared to control, A–velocity (cm/sec) was increased in study group compared to controls,

Conclusion:  myocardial ischemia and infarction may adversely affect both relaxation and compliance.one has to use parameters not affected by heart rate, and preload may alter parameters of Doppler echocardiographic indexes. However, compared to radionuclide and catheterization studies, Doppler echocardiographic method is faster, safer, non–invasive, more economical study can be done bedside without any risks to the patient which are inherent with radionuclide and catheterization techniques