Back ground: TB (tuberculosis) and HIV (Human Immuno Deficiency Virus) act in deadly synergy. HIV infection increases the risk of TB infection on exposure, progressing from latent infection to active TB, increasing the risk of death if not timely treated  and increasing the risk of recurrence even if successfully treated.

Objective: The present study was a retrospective observational hospital based study conducted   to study the relative frequency of Tuberculosis among HIV Seropositive patients attending ART centre, SVRR GG Hospital, Tirupathi.

Materials and Methods:

INCLUSION CRITERIA: Patients above the age of 12 years, both male and female patients, positive for HIV  attending ART centre, SVRRGG Hospital, Tirupathi and patients in Medical wards and TBCD wards were included in the study.  All the patients were subjected to routine and specific investigations and thorough clinical examination. Data collected was analyzed. Results:   Out of 168 patients, 74 (44%) were determined to be infected with TB. 49(66.2%) were males, and 25 (33.8%) cases were females, with male to female ratio 2:1.    Most   of patients (52.7%)   fell in the age group of 31–40. The mean age for males was 36.2 and 35.2 for females.   Among all the patients Sputum AFB (Acid Fast Bacillus) positive pulmonary TB was seen in19 (25.7%), Sputum AFB negative pulmonary TB in 21 (28.4%). In present study the mean CD4 count    was 237.27 to 167.81 cells/ micro L.

Conclusions: Present study concludes that male sex and patients of age group 30–40 years were the commonly affected population. All forms of tuberculosis were common with CD4 counts ranging from 237.27 to 167.81 cells/mm3.