BACKGROUND: Connective tissue disorders are caused by deposition of immune complexes or inherited as disorders of bone, skin, cartilage, blood vessels and basement membrane.  T   hese pregnancies are always considered as  high risk.

CASE SERIES: We present  five cases of successful pregnancy outcomes  in patients  diagnosed with connective  tissue diseases . Three cases  diagnosed with Antiphospholipid antibody syndrome were on aspirin ,heparin, progesterone supplements antenatally and postnatally on heparin have successful outcome. One case diagnosed with Systemic lupus erythematosis  was on Tab Azathioprine, Tab Chloroquine, steroids antenatally and postnatally had successful outcome. One  case diagnosed with Sjogren syndrome was on steroids before and after delivery had successful outcome.

CONCLUSION : Pregnancy with connective tissue disorders  are associated with increased  maternal and perinatal complications. Preconceptional  counseling, appropriate medication, multidisciplinary care, delivery in tertiary care hospital with specialist can result in favourable outcome.