Purpose: The objective this study was to evaluate the outcome of combined surgical therapy of peri–implantitis.

 Methods: The 32 patients involved in this study with inflammatory–destructive processes in the field of peri–implant tissues of osseointegrated implants. The patients were examined clinically and radiographically. The diagnostic parameters used for assessing peri–implantitis include clinical indices, probing pocket depth (PPD), bleeding on probing (BOP), periimplant radiography. PPD and BOP data at the re–examination were retrospectively compared to baseline data.

Results: A statistical significant reduction in both PPD and BOP were seen at all timepoints as compared with the baseline clinical measurements. Stable clinical measurements  PPD and BOP were demonstrated after 1 year the initial treatment, remaining stable during the following three years. Conservative treatment methods are effective in the treatment of peri–implant mucositis and еarly peri–implantitis. When peri–implantitis category moderate and severe effective surgical treatment combined conservative therapy.

Conclusion: Surgical regenerative treatment combined with mechanical and chemical detoxification of the implants’ surface, magneto–laser therapy and regenerative therapy using a autologous bone, xenograft, hyaluronic acid and a resorbable membrane  a reliable method for stopping and treatment  peri–implantitis.