Back ground: Gingivitis means the inflammation of the gingiva. Microbial plaque is the primary aetilogical agent for the enema of the periodontal disease however the host immune response plays a major role for the disease progression. Objective: Role of Homoeopathic Medicines in treatment of gingivitis. Methodology: An experimental study was carried out in Tanuja Dental Clinic, Andhra Pradesh, India. Thirty out patients with clinically confirmed symptomatic cases of gingivitis were entered trial and treated with Homoeopathic remedies on the basis of Homoeopathic principles. Result: The overall response of the treatment with the help of seven Homoeopathic medicines. It was observed that 24(80%) fully relieved, 4 (13.33%) partially improved and 2 (6.67%) cases not improved out of thirty patients.