The present study was carried out with an aim of evaluation of color stability of flexible denture base material after exposure of  GARAM MASALA for particular duration  using  reflectance spectrophotometer. Thirty flexible denture base material samples (15×15×2m.m.) were fabricated in this study. Thirty samples were evaluated at 0 day (baseline) before immersion and at 15 days and 30 days after immersion in garam masala solution. Color changes (ΔE) were calculated by  reflectance spectrophotometer with the use of C.I.E. L*a*b* uniform color scale. To evaluate the effect one way ANOVA test was carried out, as the results were statistically significant ( p = 0.05)  Multiple comparison test ( Tukey’s Analysis) was done subsequently. Flexible denture base material undergoes a major color change when immersed in coloring agent (Garam masala). So its use is restricted where conventional denture base resins are not preferable.