Urinary tract infection (UTI) is one of the universal forms of infectious disease in human. Culture, habits, provision of sanitation, hygiene and health care service have great influence on the incidence and bacterial profile of the UTI in different settings.

A Cross–sectional study was done on 202 non pregnant women of reproductive age group (15–45 years) in a tribal area in Eastern part of India  during July – August 2017.Clean catch midstream urine samples were collected from participants during home visit , irrespective of  sign symptoms of UTI. Among the 202 urine samples 44 samples (21.78%) showed growth. Of these 44 patients, 61.36% had no urinary symptoms.   Escherechia.coli (n=11) was found to be predominant uropathogen followed by Staphylococcus aureus (n= 7), Klebsiella sp(n=2), Morganella morganii(n=2), etc.  Amikacin (96.8%)   appeared as most effective drug both against Gram positive and Gram negative pathogenic isolates, followed by  Meropenem (93.5%), Nitrofurantoin (83.9%), Ciprofloxacin (80.6%) . Isolates showed least susceptibility to  Cotrimoxazole (51.6%) and Amoxyclav (28.57%).   Knowledge of incidence of UTI and distribution of organism along with their sensitivity pattern were essential for deciding empirical treatment of UTI of any population.