We aim to study degree of effect that yoga brings in normal subjects (Group I) as compared to hypertensive diabetics (Group II) in terms of various cardio–respiratory parameters observed every 30 days for 90 days and biochemical parameters at end of study. In Group I significant reduction in all parameters was observed. In Group II, significant reduction in weight, BMI, PR, RR, SBP, DBP, MBP, PP and TC, TG, LDL, VLDL, TC/HDL ratio, LDL/HDL ratio and highly significant reduction in FBS, PMBS along with significant increase in HDL were observed after 90 days of yoga practices. The results indicate that yoga when given in normal person and in hypertensive diabetics causes shifting of the physiological and biochemical parameters towards favorable side of the normal range.