Background: The prevalence of patients suffering from psychiatric disorder along with co–occurring substance use disorders and vice–versa are increasing through time which worsen treatment outcome and increase relapse.

Objectives:  to assess the prevalence of psychiatric comorbidities among cannabis dependent patients.

Material and Method: 40 cases of cannabis dependence who attended psychiatry opd of Gauhati Medical College were selected based on ICD 10 criteria. The psychiatric comorbidities were assessed in them using MINI INTERNATIONAL NEUROPSYCHIATRIC INTERVIEW.

Result: In our study of 40 cannabis dependent patients psychiatric comorbidities were found in 39(97.5%). The comorbidities were mood disorder in18 (45%), psychotic disorder 16 (40%), antisocial personality disorder 3 (7.5%) and anxiety disorder in 2 (5%).

Conclusion: From the present study we came to the conclusion that psychiatric comorbidities are common among cannabis dependent patients.