In frozen technique, fresh tissue is rapidly frozen, and the tissues become firm owing to ice acting as embedding medium. Thus, sections are produced without the use of dehydrating solution, clearing agent or wax embedding. Intra–operative frozen section plays an important role in the management of surgical patients and yet it must be used prudently to avoid the indiscriminate usage of this important technique. The surgeon may want to know if the margins of his resection for a malignant neoplasm are clear before closing, or an unexpected disease process may be found and require a definite diagnosis to decide what to do next, or it may be necessary to determine if the appropriate tissue has been obtained for further workup of a disease process. This can be accomplished through use of a FS. The limitations FS can be poor sampling of tissue, artefact when compared with routine tissue processing.