IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-4-14971 Original Research Paper Occurrence and pattern of dyslipidemia in type 2 diabetes mellitus and its correlation with anthropometric parameters Singhai Dr. April 2018 7 4 01 02 ABSTRACT

Background:Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. Early detection and treatment of dyslipidemia in type 2 diabetes mellitus (T2DM) can prevent risk for atherogenic cardiovascular disorder. The rationale of this study was to detect the lipid abnormality in diabetic patients in association with anthropometric parameter of obesity including Body Mass Index (BMI) and Waist circumference (WC).

Methods: Necessary data was collected from the medical archives of 100 T2DM patients (50 female and 50 male) registered in a tertiary care hospital of Madhya Pradesh.

Results: The mean ages of female and male subjects were 56.22±8.86 and 54.76±10.38 years respectively. Mean duration of diabetes was 5.19 ±5.68 years. Mean BMI of male and female patients were 27.50 ± 5.77and 29.52 ± 5.75kg/m2 respectively. Mean WC of male and female patients were 88.52 ± 12.06 and 93.86 ± 12.3 centimeter (cm) respectively.The mean values of fasting blood sugar (FBS) and postprandial blood sugar (PPBS) in females were187.08 ± 77.45 and 260.84 ± 115.73 mg/dl respectively, while mean values of FBS and PPBS in males were 176.28 ± 80.47 and 252.96 ± 99.63 mg/dl respectively. Results of serum lipids showed that the mean values for total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL–C), and low density lipoprotein cholesterol (LDL–C) in male patients were177.62 ± 51.16, 198.16 ± 97.30, 34.94 ± 8.41 and105.08 ± 40.28 mg/dl respectively. The mean values for TC, TG, HDL–C, and LDL–C in female patients were 187.66 ± 42.23, 205.00 ± 93.17, 40.00±8.5, and 108.22±31.59 mg/dl respectively. Prevalence of dyslipidemia was 96%. Negative and statistically significant correlation was found between WC and HDL–C. Positive statistically non–significant correlations were found among BMI and WC with TGs.

Conclusions:Based on the study results, it is clear that aggressive dyslipidemia management is the need of the hour in patients with diabetes. We hope our study will pave the way for future research in this area and also help the medical fraternity in consciously taking measures to address these burning issues.