IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-4-14992 Original Research Paper MACULAR GANGLION CELL LAYER THICKNESS MEASUREMENT BY SD- OCT IN NON GLAUCOMATOUS MYOPIC EYE AND ITS CORRELATION WITH SPHERICAL EQUVALENT AND AXIAL LENGTH Deepti Mujumdar Dr. Dr. Pushpa Varma Dr. April 2018 7 4 01 02 ABSTRACT

Purpose:  To evaluate macular ganglion cell layer thickness in non glaucomatous myopic eye and its correlation with spherical equivalent and axial length.

Material and methods:  A Cross sectional observational study was carried out in 50 eyes who were reported myopes. A detailed ophthalmic examination was done and participants having raised IOP and field defects were excluded. The selected candidates were subjected to ganglion cell complex study by SD–OCT and their relationship against myopic refractive equivalents and axial length was evaluated.

Result:   Eligible subjects were in the age group of 18– 35 years. Out of the 50 eyes evaluated, 40%   showed that ganglion cell layer was thinner in myopes.  Average ganglion cell layer thickness observed was 59mm ±5mm with an average axial length of23.5±2.5 mm and mean spherical equivalent of –6.00D ±4D. Females were more affected than males.

Conclusion:  The thickness of the ganglion cell complex has positive correlation with myopia and axial length. With increase in spherical equivalent and axial length, ganglion cell layer thickness decreases. There are chances of patients being diagnosed as false positive cases of glaucoma and over estimation of ganglion cell layer loss. Therefore in a patient who is diagnosed as glaucoma patient, correlation of spherical equivalent and axial length with ganglion cell layer thickness should also be considered. Though only ganglion cell layer thickness cannot be a diagnostic criterion for the diagnosis of glaucoma and should be correlated with other findings.