IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-4-15027 Original Research Paper An open label pilot study to evaluate the effectiveness of a proprietary nutraceutical formulation on elements of skin function associated with aging. Wakeman Dr. April 2018 7 4 01 02 ABSTRACT

This open label pilot study evaluated the effect of a proprietary nutraceutical formulation–Skin WithinTM–on objective measures of skin function associated with aging over 3 months. The supplement containing collagen, citrus and rosemary extract, maritime pine bark extract, vitamin C, Coenzyme Q10, astaxanthin and biotin was taken twice daily. After 84 days compared to baseline, highly statistically significant effects were observed in the 30 individuals who completed the study regarding reduction in trans–epidermal water loss and skin roughness, along with increases in hydration,elasticity, and smoothness of the skin. 29 participants also reported subjective improvements in the condition of their hair and nails. This study demonstrates that Skin Within has the potential to deliver significant benefits in skin condition and reverses objective measures of skin function associated with skin aging. A larger placebo controlled trial is now proposed.