A limited amount of systematic literature reviews on the association between malocclusion and oral health quality of life summarize inconclusive result. Therefore we conducted a systematic review and meta–analysis on the association of malocclusions with oral health status in children the concept of Oral Health–Related Quality of Life (OHRQoL) corresponds to the impact of oral health or disease on an individual’s daily functioning, well–being or overall quality of life. Aim:Impact of malocclusion on quality of life and oral health status among 12 to 15 year old children. Materials and Method:The present study was done to assess the impact of malocclusion on quality of life and oral health status among 12–15 years old children of Meerut City.  RESULT:Among the total sample of 820 subjects, (25.9%) had defined malocclusion and (23.8%) had severe malocclusion.The total OHIP score of this sample size ranged from 0 to 32.Functional limitation domain of OHIP–14 displayed highest score 3.1+1.9 CONCLUSION:Defined and severe malocclusion had impact on Oral Health related Quality of life but itshowed non–significant impact on oral health status.