IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-4-15151 Original Research Paper Partial empty sella syndrome with pan hypopituitarism leading to pericardial effusion. Choudhary Dr. RK Jha Dr. April 2018 7 4 01 02 ABSTRACT

 There have been number of leading causes of pericardial effusion but secondary hypothyroidism has rarely been described as a cause of pericardial

effusion. Here we present a case of 35 years female who presented with anasarca, shortness of breath and easy fatiguablity. Her echocardiography
revealed pericardial effusion with impending cardiac temponade. There was evidence of secondary hypothyroidism with decreased free T3 and T4
and normal TSH levels. Further detailed workup history revealed history of post–partum hemorrhage few years back with loss of menstruation and
lactation following it. Suspicion of pituitary disorder was made which was confirmed by decrease FSH, LH, prolactin levels. MRI brain confirmed
diagnosis of partial empty sella turcica syndrome. This case indicated the need to consider hypothyroidism, even central, as a possible etiology in
patients with unexplained pericardial effusion. Since Sheehan‘s can present at a variable duration after the last pregnancy it has to be considered
even if history of childbirth is remote.