50 root dentin sections were obtained from 25 extracted premolars and  divided  randomly into 5 groups of 10 samples each. Except group 1, all the other group specimens were demineralised by immersing in a demineralising solution for 96 hours at  37⁰C.  The specimens were then subjected to surface treatment with grape seed extract, silverdiamine fluoride and calcium sucrose orthophosphate complex according to the groups. The samples were stored in artificial saliva during the intervals and subjected to pH cycling and evaluated using SEM–EDAX and the results statistically compared.

     The tested remineralizing  agents showed statistically significant increase in  remineralization when compared to the demineralized group. Calcium sucrose orthophosphate showed the highest Ca/P values followed by Silver diamine flouride and grape seed extract.