In the present work an attempt has been made to find out the in vitro antitubercular activity of Cassia occidentalis L. (Caesalpiniaceae).Cassia occidentalis L. leaf and seed extracts were screened against Mycobacterium tuberculosis H37Ra and Mycobacterium bovis strains using Microplate Alamar Blue Assay.The present study revealed that Chloroform and Hexane solvent extracts of Cassia occidentalis L. leaf and seed were inactive against Mycobacterium tuberculosis H37Ra and Mycobacterium bovis strainsat a concentration of 100µg/ml.