Spleen is the largest lymphatic organ in the human body and is involved in hematological and immunological functions. The splenic lesions can be small or large, ill defined or well encapsulated or it can be infiltrating in configuration making diagnosis a difficult task. Cross sectional imaging with computed tomography is the imaging modality for evaluating splenic lesions. Most of the splenic lesions are hypodense on CT images and warrant a closer attention for differentiating benign from malignant pathologies. The authors present a series of splenic lesions and the value of computed tomography in depicting the splenic disease.