IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-5-15396 Original Research Paper A Study of hepatic enzymes status in patients with dengue infection: Preetham R.M Dr. May 2018 7 5 01 02 ABSTRACT

Dengue viral infections are known to present a diverse clinical spectrum, ranging from asymptomatic illness to severe dengue.4 The degree of liver dysfunction in children with dengue infections varies from mild injury with elevation of transminase activity, hepatomegaly (tender/non tender) to severe injury with jaundice and fulminant hepatic failure.6The elevation of liver enzymes varies according to the type of clinical presentation of dengue infection, and is more common in patients with severe dengue.Awareness of these manifestations of hepatic involvement in dengue may be helpful in arriving at early diagnosis and avoiding morbidity and mortality.

Since our hospital (Kanachur Institute of Medical Sciences) is tertiary care hospital, we do see a lot of children with dengue infections including those with atypical manifestations. So, an attempt has been made tostudy hepatic enzymes status and its prognostic significance in children with dengue virus infection.