Actinomycosis is a rare chronic inflammatory disease caused by an anaerobic actinomyces species that can rarely affect the intestine. The infection has tendency to infiltrate adjacent tissue and rarely confined to a single organ. We report the rare case of ilio–colic junction actinomycosis in a 74 year old man mimicking clinically a malignant inflammatory tumor of right colon. The patient presented with complaining of abdominal pain and lump in right iliac fossa for 1 month duration. Patient denied having previous surgery. CT abdomen suggestive of IC junction tumor. Patient underwent for laparoscopic assisted right hemicolectomy. Histopathological examination revealed IC junction actinomycosis   Preoperative diagnosis in colon actinomycosis is difficult to achieve..