BACKGROUND: Isoamyl 2–cyanoacrylate is a tissue adhesive, which can be used for the closure of the incised wounds to overcome the problems associated with conventional suture materials like silk. They are well accepted owing to their properties including bacteriostatic effect, hemostatic effect, biodegradation, biocompatibility, easy manipulation and reduced surgical time.

AIM: To assess the effect of amcrylate and silk suture on wound healing and patient satisfaction following periodontal flap surgery.

METHODOLOGY: 20 periodontal flap surgeries was carried out on 10 patients. Flap approximation was done by silk suture (Group A) and cyanoacrylate adhesive(Group B) in a split mouth design. At 7^th day of surgery plaque index and healing index was evaluated. Patient satisfaction was assessed by severity of pain and bleeding by visual analogue scale.

RESULTS:Cyanoacrylate group demonstrated a statistically significant lesser mean plaque score of 0.10 ± 0.00 as compared to suture group with  mean score of 1.46 ± 0.73, at P<0.001 as seen by independent student t test. Cyanoacrylate group showed statistically significant VAS response for bleeding and there was better healing response in cyanoacrylate group.

CONCLUSION: This study suggested that, efficacy of cyanoacrylate & suturing in wound closure were similar in the severity of pain but use of cyanoacrylate showed better early healing, hemostasis and less plaque score.