IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-5-15509 Original Research Paper Antimicrobial activity of Moringa oleifera lam. Extract against some Food-Borne Microorganisms and some Human Pathogens. Dr. Timothy O. Bamgbose Dr. May 2018 7 5 01 02 ABSTRACT

Moringa oleifera is a tropical tree whose many economic applications and facility of propagation are arousing growing international interest.

Various parts of the plant such as the leaves, roots, seed, bark, fruit, possess antitumor, cholesterol–lowering, antibacterial and antifungal activities.Itsparts are being used in water purification processes by flocculating Gram–positive and Gram–negative bacterial cells.

 

The significance ofthis investigation suggests that the extracts and juice of M. oleifera Lam. contain antibacterial agent for developing new pharmaceuticals tocontrol studied human pathogenic bacteria responsible for severe illness.The various parts of the plant were dried and grounded into coarse powder and extracted in suitable solvent. The antimicrobial activity of the compounds from Moringa oleifera, were measured by disk diffusion method.The extracts were found to inhibit the growth of Gram–positive bacteria as well as Gram–negative bacteria. All the extracts showed varying degrees of antimicrobial activity on the microorganism tested.These findings suggest a new pathway in elucidating a potent antimicrobial agent from Moringa oleifera. This study indicates that the plant contains antimicrobial compound that can be further developed as phyto–medicine for the therapy of infection and drug development.

The study was designed to investigate antibacterial gal activity of Methanol extract

from the leaf of Moringa oleifera. The extract were screened for antibacterial activity by

disk diffusion method. The leaf extract of Moringa oleifera showed a broad–spectrum antibacterial activity against different pathogens. The maximum zone of inhibition was seen in Pseudomonas aeruginosa at 100µg concentration, while the lowest was seen in Proteus species at 30µg concentration.