Introduction and Aim: Miscarriage represents a common problem that occurs in     

the first trimester of pregnancy. There is no general agreement on the value of submitting

tissues from uterine evacuation in cases of miscarriage for histopathological examination.

This study aimed to evaluate the role of histopathological examination in cases of         

first–trimester miscarriage and evaluate the clinical and histopathological findings relating to surgical uterine evacuation in first trimester miscarriages.

Methods: The Study was done in military hospital Shillongretrospectively fromOctober 2015 to march 2018 ,in which total of 275tissue samples were studied,obtained via surgical uterine evacuation in patients who were having a history of conception up to 12 month period with the clinical data including age, parity, gestational age, clinical diagnosis, and

other relevant information were collected .

Results: Incomplete miscarriage was the commonest type of miscarriage and constituted

65.3% (179)of the studied group and surgical evacuation was the most common method of       

termination. The histopathology reports confirmed the pregnancy in all patients and      

revealed retained product of normal pregnancy in 238 (86.54%) cases, partial mole in       

5 (1.82%) patients, complete hydatidiform mole in one (0.36%) case, decidual reaction/Arias stella reaction in  21 (7.64%) cases and no product of conception in 10 (3.64%) cases .

Conclusion: Clinical and Histopathological examination of the products of conception is an important method in detecting undiagnosed molar pregnancy that needs special follow–up , further ressurective measures andmanagement.