The femoral artery is a large artery in thigh and the main arterial supply to the lower limb& is easily accessible to catheterization. The femoral &profundafemoris artery is used for arteriography, ultrasound and Doppler imaging, digital substraction angiography and magnetic resonance imaging. The knowledge of femoral artery is important to avoid complication like arteriovenous fistula during transfemoral approach, also procedure like hemodialysis for renal failure and embolization of arteries of the specific regions of the body. The study was conducted on 50 (36male and 14 female) lower limbs from adult human cadavers aging from 30–70 years used for routine dissection procedure for UG students.Origin of femoral artery in 14% cases its lateral & in 10 % cases its medial to in relation to mid inguinal point; similarly in 8% cases origin of superficial external pudendal& superficial epigastric arising from the common trunk. In the origin of profundafemoris from femoral in 12% cases it was posterolateral & in 4% cases it was posterior origin. In the study it was also observed that in 4%cases lateral circumflex femoral & in 6% cases medial circumflex femoral artery arising from femoral artery. Based on these variations it concluded that femoral artery has a complex variation in its origin, relationship with its branching patterns which is very useful to the cardiologists, radiologists, plastic surgeons and vascular surgeons in the future.