IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-6-15751 Original Research Paper Pt/ TiO2 CATALYSTS IN THERAPEUTIC APPLICATIONS Omar Contreras Lopez Dr. Fernando Pastrana Dr. June 2018 7 6 01 02 ABSTRACT

Nanotechnology involved in the design, synthesis, characterization, and application of materials and devices whose functional organization is at the nanoscale. Cancer is one of the leading causes of death worldwide; it is a condition in which the use of nanotechnology has been studied for diagnostic and therapeutic purposes. The conventional approach to treatment includes chemotherapy and radiotherapy, which is limited by its toxicity to neighboring normal cells, the resistance of cancer cells and the proliferation of tumors due to the presence of stem cells. In this study we determine the effect of platinum catalysts supported on nanoparticles (NPs) of titanium dioxide (TiO2) in tumor cells. Transmission electron microscopy and fluorescence microscopy studies confirm a synergistic effect between the inorganic oxide support of TiO2 and the platinum drug, which reduces the rate of tumor growth due to the apoptotic effect of the tumor cells without associated adverse events.