IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-6-15755 Original Research Paper PSORIASIS AND VIRAL HEPATITIS: A RETROSPECTIVE STUDY FROM TURKEY WITH 1017 PSORIATIC PATIENTS At?l AVCI Dr. June 2018 7 6 01 02 ABSTRACT

 Objectives: In this research we investigated the relation of HBsAg, anti–HBs and anti–HCV with psoriasis.

Methods: This research was carried out by retrospective screening of viral hepatitis markers from the files of psoriatic patients in the dermatology
department. Data of 1017 psoriasis patients who applied between January 2010 and January 2018 could be reviewed. Hepatitis markers of 243
patients were used as controls.
Results: HBsAg was positive in 2.6% of the patients (n=26). This rate was 2.6% (n=15) in males and 2.5% (n=11) was in females (p=0.937). In the
control group, HBsAg was positive in 3.7% (n=9) (p=0.328). 30.3% (n=308) of the patients had anti–HBs antibody positivity. Anti–HBs positivity
in controls was 44.9% (n=109) (p<0.001). The mean age of patients with anti–HBs antibody positivity was 45.5±16.5 years, while the mean age of
patients with anti–HBs antibodies was 47.5±13.9 years (p<0.048). Anti–HCV positivity was found in 1.0% of the patients and was 2.1% (n=5) in
controls (p=0.165). The mean age of patients with anti–HCV antibody positivity was 70±13.8 years, while it was 46.7±14.6 years in patients with
negative anti–HCV antibodies (p<0.001).
Conclusion: The incidence of HBV and HCV in psoriatic patients was not different from the normal population. AntiHBs antibody positivity and
antiHCV positivity are not different according to sex, but may show a significant difference in age distribution.