in size of the LV(left ventricle) cavity ( in the long–axis direction). Thus, it can be interpreted as the volume change during ejection and therefore a

close association between the long–axis shortening and ejection fraction (EF) has been suggested in different patient groups with normal or reduced

LV function.

BACKGROUND:Reduced MAPSE reflects impaired longitudinal function and thus provides complementary information to ejection fraction

(EF), which represents the global result of both longitudinal and circumferential contraction1. Reduced long–axis deformation results from

dysfunctional or stressed longitudinal myofibers due to ischaemia, fibrosis, or increased wall stress.MAPSE has been suggested as a surrogate

measurement for LV function.

METHODS: Prospective analysis of 111 patients came to our OPD by two–dimensional transthoracic echocardiography was carried out.

MAPSE and ejection fraction measured by qualitative visual inspection, M–mode (medial and lateral septal annulus), modifiedSimpson‘smethod

.MAPSE was compared against ejection fraction by modified Simpson‘susing Standard statistical analysis.

RESULTS:There are 90 male and 21 femalepatients included in these studies. These patient are divided in to four category based on ejection

fraction which includes, 1) EF less than 30 % EF(N=20) 2)EF 30–40 %(N=27) 3)EF 40–50%(N=10) 4)more than 50 %(N=54).MAPSE of the

groups are 1)less than 30%–mean MAPSE=5.3, 2)30–40%EF mean MAPSE =7.52, 3) 40–50 %EF mean MAPSE=9.8 4)more than 50 % EF mean

MAPSE=14.5. P value is 0.001.MAPSE cutoff value of less than or equal to 5 provided the best balanced predict EF <30%.From these study

MAPSE less than 14 suggested presence of LV dysfunction.

CONCLUSION:MAPSE measurement is still especially helpful to evaluate LV systolic function in case of poor sonographic windows, since

good imaging quality is required for most of the modern echocardiographic techniques.