IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-7-15880 Original Research Paper INCIDENCE OF CARDIOVASCULAR DISEASES IN TYPE 2 DIABETES MELLITUS PATIENTS Pasha Dr. July 2018 7 7 01 02 ABSTRACT

Type 2 Diabetes Mellitus is a medical condition characterized by an elevation of blood glucose level, this metabolic disorder will taken place as a result of either insulin resistance and/or insulin deficiency. It is the most prevalent chronicmetabolic disorder worldwide.Type 2Diabetes Mellitus isthe significantcause of premature morbidity and mortality imposingenormous socioeconomic burden globally. As per the currentprevalence and trend of T2DM, International Diabetes Federation (IDF) predicted 592 million people will have T2DM by 2035 worldwide. Prevalence of T2DM is escalating at rapid pace in Indiadue to westernization of lifestyle. As per IDF report, the prevalence ofT2DM will increase to 101.2 million by 2030 among Indians. Type 2 diabetes mellitus istypically a chronic disease associated with a ten–year–shorter life expectancy. This is partly due to a number of complications with which it is associated, including two to four times the risk of cardiovascular disease, including ischemic heart disease and stroke; a 20–fold increase in lower limb amputations, and increased rates of hospitalizations. In the developed world, and increasingly elsewhere, type 2 diabetes mellitus is the largest cause of non–traumatic blindness and kidney failure. It has also been associated with an increased risk of cognitive dysfunction and dementia through disease processes such as Alzheimer‘s disease and vascular dementia.The contemporary associations of type 2 diabetes mellitus with a wide range of incident cardiovascular diseases have been compared in this study. Results showed that Type 2 diabetes mellitus was positively associated with peripheral arterial disease, ischaemic stroke, heart failure, and non–fatal myocardial infarction, but was inversely associated with abdominal aortic aneurysm and subarachnoid haemorrhage, and not associated with arrhythmia or sudden cardiac death.Type 2 DM is a metabolic disease that can be prevented through lifestyle modification, diet control, and control of overweight and obesity. ovel drugs are being developed, yet no cure is available in sight for the disease, despite new insight into the pathophysiology of the disease. Management should be tailored to improve the quality of life of individuals with type 2 DM.