IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-7-15910 Original Research Paper Effects of single dose of intravenous Dexmedetomidine on Hyperbaric Bupivacaine Spinal Anaesthesia : A randomized study ( Col ) Pradeep Pendyala Dr. July 2018 7 7 01 02 ABSTRACT

Background :
The present study is designed to evaluate the effect of intravenous dexmedetomidine on spinal anesthesia with 0.5% of hyperbaric bupivacaine.

Objective:

To evaluate the effect of intravenous dexmedetomidine on sensory regression, hemodynamic profile, level of sedation and postoperative analgesia.

Materials and Methods:

Sixty patients of American Society of Anaesthesiologists (ASA) physical status I/II patients undergoing elective surgeries under spinal anaesthesia were randomized into two groups of 30 each. Immediately after subarachnoid block with 3 ml of 0.5% hyperbaric bupivacaine, patients in group D received a loading dose of 0.5μg/kg of dexmedetomidine intravenously over a period of ten minutes,  whereas, patients in group C received an equivalent quantity of normal saline.