IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-7-16018 Original Research Paper Grave's disease: Study of Clinical presentation, Hormonal, Biochemical and Radiological investigations along with cytological parameters Aarti P Pachrupe Dr. Dr Vikas Kavishwar Dr. July 2018 7 7 01 02 ABSTRACT

Grave’s disease accounts for 60–80% cases of thyrotoxicosis. Diagnosis of Grave’s Disease is based on clinical findings, thyroid function tests, USG, radioactive iodine thyroid scan and presence of anti–thyroidal antibodies. Fine needle aspiration cytology of thyroid is necessary in selected cases. We studied cytological findings in 25 cases ofGraves’ disease, where FNAC was indicated because of nodularity or cold areas on scan. All cases had elevated serum T3, T4 with high anti–TPO titers seen in majority of cases.Fire flares and lacy cytoplasm were significant cytomorphological features. Combined evaluation of clinical presentation, hormonal status, anti–thyroid antibodies and RAIU scans along with cytological parameters can correctly interpret Grave’s disease.