Background–Primary carcinoma of the vagina is rare malignancy of female genital tract

which constitutes 1–2% of all gynecological malignancies. The peak incidence is in the

sixth and seventh decades of life. Approximately 50% of vaginal cancers arises on the

posterior wall of the upper one third of the vagina.

The majority of primary vaginal malignancies are squamous cell carcinoma constitutes

85% and the remaining are adenocarcinoma about 15 %. Histological patterns of

adenocarcinoma include clear cell carcinoma, adenosquamous, papillary and undifferentiated. Other types are melanomas, sarcomas and unspecified types.

Case report–We report a case of primary vaginal papillary adenocarcinoma in a 61

years old woman presented with symptoms of persistent andprofuse clear vaginal discharge since 7 months, vaginal bleeding since 2 months andpain in lower abdominal region since 1 month and USG showed ill defined soft tissuemassseen in lower one third of vagina.

CT scan suggestive of large ill defined mass approximately 4.8 X 2 .7 cm seen in lower

vagina and few subcentrimetric pericaecal and mesenteric lymph nodes seen largest

measuring 9mm in short axis.Immunohistochemistry showed CK20, DUPAN 2 positive and CA 125, CK7, serumCEA negative.

Conclusion– This case reported here for its rare presentation in all gynecological

Malignancies.