IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-7-16125 Original Research Paper Case Control Study of Autonomic Function Tests in Rheumatoid Arthritis female patients Deepak Goyal Dr. Dr Chetanya Prakash Gupta Dr. July 2018 7 7 01 02 ABSTRACT

Background – In Rheumatoid Arthritis (RA) patients’ involvement of autonomic nervous system has rarely been studied1.

Objective – Evaluation of cardiovascular autonomic neuropathy (CAN) in RA patients.

Material and methods – 45 RA female patients(age group 35–45 years) along with 45 age and BMI matched female controls were evaluated by: Valsalva ratio andLF/HF ratio recorded by CAN Win analysis system (window based) and Polyrite D based on EKG respectively.  Statistical analysis was performed using SPSS software version 20 and Z–test was used to derive the level of significance.

Results –The mean Valsalva ratio was found lower (p value <0.01) whereas meanLF/HF ratio was found higher (p value<0.001) in RA patients as compared to control group.

Conclusion–Cardiovascular autonomic functions are found deranged In RA patients. Early detection of cardiac autonomic neuropathy in RA patients can help in timely management and prevention of morbidity.